Could a biocomputer made from human brain cells play DOOM?

In 2022, the wetware wizards of Cortical Labs taught neurons grown from stem cells to play the video game Pong. Now, four years later, the neurons have a much more refined pastime. They sit in the CL2 biocomputer and play Doom in the name of science and the development of biological neural networks.

It’s been about a year since we at OSLU wrote about the first commercial biological computer, the CL1, built by the Australian Cortical Labs. The CL1 biocomputer grows human neurons that grow on a silicon chip. The chip sends them and also receives electrical impulses from them. The neurons come from stem cells.

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NVIDIA Project DIGITS With New GB10 Superchip Debuts as World’s Smallest AI Supercomputer Capable of Running 200B-Parameter Models

CES—NVIDIA today unveiled NVIDIA® Project DIGITS, a personal AI supercomputer that provides AI researchers, data scientists and students worldwide with access to the power of the NVIDIA Grace Blackwell platform.

Project DIGITS features the new NVIDIA GB10 Grace Blackwell Superchip, offering a petaflop of AI computing performance for prototyping, fine-tuning and running large AI models.

With Project DIGITS, users can develop and run inference on models using their own desktop system, then seamlessly deploy the models on accelerated cloud or data center infrastructure.

“AI will be mainstream in every application for every industry. With Project DIGITS, the Grace Blackwell Superchip comes to millions of developers,” said Jensen Huang, founder and CEO of NVIDIA. “Placing an AI supercomputer on the desks of every data scientist, AI researcher and student empowers them to engage and shape the age of AI.”

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World’s first “Synthetic Biological Intelligence” runs on living human cells

The world’s first “biological computer” that fuses human brain cells with silicon hardware to form fluid neural networks has been commercially launched, ushering in a new age of AI technology. The CL1, from Australian company Cortical Labs, offers a whole new kind of computing intelligence – one that’s more dynamic, sustainable and energy efficient than any AI that currently exists – and we will start to see its potential when it’s in users’ hands in the coming months.

Body in a box: The CL1 doesn’t require an external computer Cortical Labs

Known as a Synthetic Biological Intelligence (SBI), Cortical’s CL1 system was officially launched in Barcelona on March 2, 2025, and is expected to be a game-changer for science and medical research. The human-cell neural networks that form on the silicon “chip” are essentially an ever-evolving organic computer, and the engineers behind it say it learns so quickly and flexibly that it completely outpaces the silicon-based AI chips used to train existing large language models (LLMs) like ChatGPT.

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World’s first scalable, connected, photonic quantum computer prototype developed

A team of engineers, physicists and computer specialists at Canadian company, Xanadu Quantum Technologies Inc., has unveiled what they describe as the world’s first scalable, connected, photonic quantum computer prototype.

Schematic diagram of the Aurora system and main modules. Credit: Nature (2025).

In their paper published in the journal Nature, the group describes how they designed and built their modularized quantum computer, and how it can be easily scaled to virtually any desired size.

As scientists around the world continue to work toward the development of a truly useful quantum computer, makers of such machines continue to come up with design ideas. In this new effort, the research team built a quantum computer based on a modular design. Their idea was to build a single basic box using just a few qubits for the simplest of applications. As the need arises, another box can be added, then another and another—with all the boxes working together like a network, as a single computer.

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